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Accueil > Actualités

Salle de réunion bat. HERBIER

Lundi 22/06/15 - 11h

Aleksandre Japaridze, EPFL-SB-IPSB-LPMV, Lausanne, Suisse

"Hyperplectonemes, novel type of DNA structures"

Abstract :
"Bacterial chromatin is a compact and ordered structure. Despite the clear link between DNA supercoiling and compaction, the global role of supercoiling in chromatin organisation remains less understood.
In order to address this question we have used Atomic Force Microscopy on large supercoiled DNA (20kb-45kb).We were interested how the overall morphology and organisation of the DNA would change with increasing DNA contour length at different levels of supercoiling and presence of nucleoid associated proteins."